Prof. MD. Ayşe BİLGİHAN
Prof. MD. Ayşe BİLGİHAN

Prof. MD. Ayşe BİLGİHAN

Medical Biochemistry

+90 552 039 04 86

MAKE AN APPOINTMENT

Resume

Prof. MD. Ayşe BİLGİHAN

  • Medical Biochemistry
  • Ufuk University Dr.Rıdvan Aegean Hospital
  • +90 312 204 42 41
  • ayse.bilgihan@ufuk.edu.tr

  
Medical school and year of graduation:

Gazi University Faculty of Medicine 1983-1989  
Place and year of study in the specialty:

  • Gazi University Faculty of Medicine Department of Medical Biochemistry 1989-1992  
  • Professional Experience
  •  Gazi University Faculty of Medicine Department of Medical Biochemistry, Assoc.Prof. MD. 1989-1992
  •  Gazi University Faculty of Medicine Department of Medical Biochemistry , MD. 1992-1995  
  •  Gazi University Faculty of Medicine Department of Medical Biochemistry, Asst. Prof. MD 1995-1997  
  •  Gazi University Faculty of Medicine Department of Medical Biochemistry, Assoc. Prof. MD 1997-2003   
  • Gazi University Faculty of Medicine Department of Medical Biochemistry , Prof.MD. 2003-2017
  • Gazi University Faculty of Medicine Department of Medical Biochemistry , Prof.MD. 2017-Present

Guided Master's and doctoral theses: 

 

Master's Theses:

  • ÖZEL     Ümmühani (Bio.)“Kolelityazisli Olgularda Serum Bakır, Çinko Değerleri ve Superoksit Dismutaz Aktivitesi” Yüksek Lisans Tezi, Gazi Üniversitesi Sağlık Bilimleri Enstitüsü, Biyokimya Anabilim Dalı (2000), 70 s.
  • MERTOĞLU Öznur (Bio.) “İyonize Radyasyon Uygulanan Kobaylarda Serum Total Malondialdehit Düzeyleri ve Superoksit Dismutaz Aktivitesi” Yüksek Lisans Tezi, Gazi Üniversitesi Sağlık Bilimleri Enstitüsü, Biyokimya Anabilim Dalı (2002), 79 s.
  • ÖZSAÇMACI Özge (Bio.) “Oksidatif Stres belirteçlerinin ve Hyaluronik Asitin Koroner Arter Hastalığının Anjiografik Yaygınlık ve Ciddiyeti İle İlişkisi” Yüksek Lisans Tezi, Gazi Üniversitesi Sağlık Bilimleri Enstitüsü, Biyokimya Anabilim Dalı (2013), 119 s.
  • MURATOĞLU Suzan (Bio) “Nonalkolik Yağlı karaciğer Hastalığı Tanılı Bireylerde Konvansiyonel İnflamasyon ve Oksidatif Stres Belirteçlerinin Düzeyleri” Yüksek Lisans Tezi, Gazi Üniversitesi Sağlık Bilimleri Enstitüsü, Biyokimya Anabilim Dalı (2014), 90 s

Doctoral and Specialty Theses in Medicine:

  • YİS    M.Özgür (Araş.Gör.Dr.)“Tavşanlarda Excimer Laser Keratektomi Sonrası Kornea Glutatyon Peroksidaz Aktiviteleri ve Humor Aköz Selenyum Düzeyleri” Tıpta Uzmanlık Tezi, Gazi Üniversitesi Tıp Fakültesi,   Biyokimya Anabilim Dalı (2000), 65 s.
  • GÜNEY Yıldız (Araş.Gör.Dr.) “Farklı Dozlardaki İyonize Radyasyonun Kobay Beyin Dokusunda Oksidan  ve Antioksidan Sistemlere Etkisi” Doktora Tezi, Gazi   Üniversitesi Sağlık Bilimleri  Enstitüsü, Biyokimya Anabilim Dalı (2002), 89 s.
  • GÖKTAŞ U.Bülent (Araş.Gör.Dr.), “Postmenapozal Dönemde Oksidatif Stres;Aopp(İleri Düzey Protein Oksidasyonu) ve Lipit Peroksidasyonu” Uzmanlık Tezi,  Gazi Üniversitesi Tıp Fakültesi, Tıbbi Biyokimya Anabilim dalı, (2004), 75 s.
  • ÖZEL     Ümmühani (Bio.), “Rat Beyin Dokusunda Etanolle İndüklenen Oksidatif Strese Antioksidan Olan Karnozinin Etkileri” Doktora Tezi, Gazi Üniversitesi Sağlık Bilimleri Enstitüsü, Tıbbi Biyokimya Anabilim dalı (2004), 84 s.
  • ÇAĞLAR Öznur Mertoğlu (Bio.), “Rat Karaciğer Dokusunda Etanolle İndüklenen Oksidatif Strese Çinkonun Etkileri” Doktora Tezi. Gazi Üniversitesi Sağlık Bilimleri Enstitüsü, Tıbbi Biyokimya Anabilim dalı (2006), 105 s.
  • DEMİREL Özlem Özbaş(Araş.Gör.Dr.) “Ratlarda Farklı Dozlarda Uygulanan Çinkonun Çeşitli Dokularda Oksidan-Antioksidan Sisteme Etkileri” Uzmanlık Tezi, Gazi Üniversitesi Tıp Fakültesi, Tıbbi Biyokimya Anabilim dalı, (2007), 94 s.
  • ERÇİN   Uğur (Araş Gör.Dr.) “Koroner Arter Hastalığında Kanda Oksidatif Stres Parametreleri ve Selenyum Düzeylerinin Klinik Bulgularla İlişkisi” Uzmanlık Tezi, Gazi Üniversitesi Tıp Fakültesi, Tıbbi Biyokimya Anabilim dalı, (2010), 193 s.
  • ERKAN Aycan Fahri (Uz.Dr.) “Mast Hücre Triptazı ve Oksidatif Stres Parametrelerinin Koroner Arter Hastalığının  Klinik ve Anjiografik Bulguları ile İlişkisi” Doktora Tezi, Gazi Üniversitesi Sağlık Bilimleri Enstitüsü, Tıbbi Biyokimya Anabilim dalı (2011), 74 s.
  • ÖKSÜZ Naki  (Araş.Gör.Dr.)“Diz Osteoartriti Olgularında Farklı Egzersiz Tedavilerinin Kan Oksidatif Stres Parametrelerine Etkisi” Uzmanlık Tezi, Gazi Üniversitesi Tıp Fakültesi, Tıbbi Biyokimya Anabilim dalı, (2014), 71 s.

Publications:
    Articles published in international peer-reviewed journals (SCI & SSCI & Arts and Humanities) 
1-Effects of acut swimming exercise on muscle and erythrocyte malondialdehyde, serum myoglobin and plasma ascorbic acid concentration. (SCI)  
Koz M, Erbaş D, Bilgihan A, Arıcıoğlu A.
Can. J Physiol. Pharmacol. 70:1392-1395,1992

2-The effect of EGb 761 on retinal lipid peroxidation and glutathione peroxidase level in experimental lens induced uveitis. (SCI-Exp) 
Bilgihan A, Arıcıoğlu A, Bilgihan K, Önol M , Hasanreisoğlu B, Türközkan N.
Int.Ophthalmol 18:21-24,1994

3-Comparison of uveitis induced by interleukin-8(IL-8) and endotoxin in rabbits. (SCI)
Akduman L, Kaplan H.J, Ataoğlu Ö, Or M, Bilgihan A, Hasanreisoğlu B.
Ocular Immunology and Inflammation 4:223-229,1994
4-Antioxidative role of ocular melanin pigment in the model of lens induced uveitis. (SCI) 
Bilgihan A, Bilgihan K, Akata F, Arıcıoğlu A, Hasanreisoğlu B.
Free Radical Biology and Medicine 19(6):883-885,1995

5-Serum alkaline phosphatase, calcium and phosphate levels following clinical use of natural coral. (SCI-Exp) 
Alpaslan G, Alpaslan C, Bilgihan A, Yamalık K.
Australian Dental Journal 40(5):327-329,1995

6-Effects of hyper-and hypo-thyroidism on oxidative stress of the eye in experimental acute anterior uveitis. (SCI) 
Bilgihan K, Bilgihan A, Diker Ş, Ataoğlu Ö, Dolapçı M, Akata F, Hasanreisoğlu B, Türközkan N.
Acta Ophthalmol.Scand.74:41-43,1996

7-The effects of 2-chloroadenosine and deoxycoformycin  on the ATP level and Na-K ATP ase activity in experimental brain ischemia of gerbil. (SCI-Exp)
Türközkan N, Bilgihan A, Çaycı B, Doğulu F, Aykol Ş.
Neurological Research 18:345-348,1996 

8-Excimer laser corneal surgery and free oxygen radicals. (SCI) 
Bilgihan K, Bilgihan A, Akata F, Hasanreisoğlu B,Türközkan N.
Jpn J. Ophthalmol 40:154-157,1996

9-The effect of 2-chloroadenosine on lipid peroxide level during experimental cerebral ischemia-reperfusion in gerbils. (SCI) 
Yavuz Ö, Türközkan N, Bilgihan A, Doğulu F, Aykol Ş.
Free Radical Biology and Medicine 22(1):337-341,1997

10-Aqueous transforming growth factor-beta-1 levels in rabbit eyes after excimer laser photoablation(SCI)
Bilgihan K, Gürelik G, Okur H, Bilgihan A, Hasanreisoğlu B, İmir T. 
Ophthalmologica 211:380-383,1997

11-Pentoxifylline inhibits overflow and reduces intestinal reperfusion injury. (SCI)
Savaş C, Aras T, Çakmak M, Bilgihan A, Ataoğlu O, Türközkan N, Ozguner F, Yucesan S, Dindar H.
Journal of Pediatric Surgery 32(6):905-910,1997

12-Changes in blood haemorheological parameters after submaximal exercise in trained and untrained subjects. (SCI)
Gürcan N, Erbaş D, Ergen E, Bilgihan A, Dündar S, Arıcıoğlu A, Dikmenoğlu N.
Physiological Research 47:23-27,1998


13-Corneal aldehyde dehydrogenase and glutathione-S-transferase activity after excimer laser keratectomy in guinea pigs. (SCI) 
Bilgihan K, Bilgihan A, Hasanreisoğlu B, Türközkan N.
Br J Ophthalmol 82:300-302,1998

14-Cytoprotective effect of trimetazidine on 60 minutes of intestinal ischemia reperfusion injury in rats. (SCI)
Tetik C, Özden A, Calli N, Bilgihan A, Bostancı B, Yis Ö, Bayramoğlu H. 
Transpl Int. 12(2): 108-112 ,1999 

15-Acute corneal necrosis after excimer laser keratectomy for hyperopia. (SCI)
Bilgihan K, Adiguzel U, Bilgihan A, Akata F, Hasanreisoglu B.
Ophthalmology 107(2):225-6,2000 (Editöre Mektup)

16- Effect of arthrocentesis and sodium hyaluronate injection on nitrite,nitrate and thiobarbituric acid-reactive substance levels in the snovial fluid (SCI) 
Alpaslan C, Bilgihan A, Alpaslan G, Güner B, Yis Ö, Erbaş D.
Oral Surgery,Oral Medicine,Oral Pathology,Oral Radiology and Endodontics,
89;686-690,2000

17--Topical vitamin E and hydrocortisone acetate treatment after photorefractive keratectomy. (SCI) 
Bilgihan K, Ozdek S, Ozoğul C, Gurelik G, Bilgihan A, Hasanreisoğlu B. 
Eye 14;231-37,2000 

18-Effect of high dose lidocaine treatment on superoxide dismutase and malondialdehyde levels in seven diabetic patients. (SCI-Exp) 
Çelebi H, Bozkırlı F,Günaydın B, Bilgihan A.
Reg Anesth Pain Med. 25;279-282,2000

19- Ascorbic acid levels in human tears after photorefractive keratectomy, transepithelial photorefractive keratectomy, and laser in situ keratomileusis. (SCI) 
Bilgihan A, Bilgihan K, Toklu Y, Konuk O, Yis O, Hasanreisoglu B
J Cataract Refract Surg 27(4);585-8, 2001 

20-The effect of excimer laser keratectomy on corneal glutathione peroxidase activities and aqueous humor selenium levels in rabbits. (SCI) 
Yis O, Bilgihan A, Bilgihan K, Yis S, Hasanreisoglu B.
Graefes Arch Clin Exp Ophthalmol 240(6):499-502, 2002

21-Keratocyte apoptosis and corneal antioxidant enzyme activities after refractive corneal surgery. (SCI) Bilgihan K, Bilgihan A, Adiguzel U, Sezer C, Yis O, Akyol G, Hasanreisoglu B. 
Eye 16(1):63-8, 2002

22-Pentoxifylline attenuates reperfusion injury in testicular torsion. (SCI)
Savas C, Dindar H, Bilgihan A, Ataoglu O, Yucesan S. 
Scand J Urol Nephrol  36(1):65-70, 2002

23-Antithrombin III prevents deleterious effects of remote ischemia-reperfusion injury on healing of colonic anastomoses. (SCI) 
Tekin K, Aytekin F, Özden A, Bilgihan A, Erdem E, Sungurtekin U, Güney Y.
The American Journal of Surgery 184:160-165, 2002

24-The effect of excimer laser keratectomy on corneal glutathione-related enzymes in rabbits. (SCI) 
Bilgihan A, Bilgihan K, Yis Ö, Şafak Yis N, Hasanreisoğlu B.
Free Radical Research 37(4):399-403, 2003  (Başlıca Araştırma Eseri)

25- Antioxidant tolerance of kidney after irradiation. (SCI-Exp)
Bukan N, Güney Y, Hiçsönmez A, Bilgihan A.
Indian Journal of Experimental Biology 41:267-269,2003 

26- Effects of topical vitamin E on corneal superoxide dismutase, glutathione peroxidase activities and polymorphonuclear leucocyte infltration after photorefractive keratectomy. (SCI) 
Bilgihan A, Bilgihan K, Yis Ö, Sezer C, Akyol G, Hasanreisoğlu B.
Acta Ophthalmologica 81(2):177-180,2003

27- The serum levels of vitamins A,C,E, beta karoten, selenium and zinc in patients with Behçet’s disease: A controlled study. (SCI) 
Erel A, Özsoy E, Biberoğlu G, Bilgihan A, Hasanoğlu A, Yis M.Ö, Atahan Ç,Oruk Ş.
Biol Trace Elem Res. 95(2):97-106, 2003

28-Changes in serum selenium, copper, zinc levels and cu/zn ratio in patients with pulmonary tuberculosis during therapy. (SCI) 
Ciftci TU, Ciftci B, Yis O, Guney Y, Bilgihan A, Ogretensoy M.
Biol Trace Elem Res. 95(1):65-71, 2003

29- Intestinal ischemia-reperfusion injury augments intestinal mucosal injury and bacterial translocation in jaundiced rats. (SCI) 
Yüksek Y.N, Koloğlu M, Dağlar G, Doğanay M, Dolapcı I, Bilgihan A, Dolapcı M, Kama N.A.
Hepatogastroenterology. 2004;51(55):171-5.

30-Lipid peroxidation and antioxidant activity in patients in labor with nonreassuring fetal status. (SCI) 
Dede FS, Guney Y, Dede H, Koca C, Dilbaz B, Bilgihan A.
Eur J Obstet Gynecol Reprod Biol. 2006,124(1):27-31.

31-Melatonin prevents inflammation and oxidative stress caused by abdominopelvic and total body irradiation of rat small intestine. (SCI) 
Guney Y, Hicsonmez A, Uluoglu C, Guney HZ, Ozel Turkcu U, Take G, Yucel B, Caglar G, Bilgihan A, Erdogan D, Nalca Andrieu M, Kurtman C, Zengil H.
Braz J Med Biol Res. 2007 Oct;40(10):1305-14. Epub 2007 Jul 31. 

32-A possible mechanism for transpupillary thermotherapy: nitric-oxide-related cellular  damage. (SCI)
Ozdek S, Urgancioglu B, Turkcu UO, Bilgihan A.
Can J Ophthalmol. 2007 Aug;42(4):609-12

33- Methimazole protects lungs during hepatic ischemia-reperfusion injury in rats: an effect not induced by hypothyroidism. (SCI) 
Tütüncü T, Demirci C, Gözalan U, Yüksek YN, Bilgihan A, Kama NA
J Gastroenterol Hepatol. 2007 May;22(5):704-9. 

34- The effects of duration of CO2 pneumoperitoneum on colonic anastomosis. (SCI-Exp) 
Ozer I, Ulas M, Ercan M, Ozogul YB, Zengin N, Bostanci EB, Ozel U, Bilgihan A, Akoglu M.
J Invest Surg. 2008 Jul-Aug;21(4):177-81.

35- Oxidative stress and antioxidant activity in orbital fibroadipose tissue in Graves'   ophthalmopathy. (SCI) 
Hondur A, Konuk O, Dincel AS, Bilgihan A, Unal M, Hasanreisoglu B.
Curr Eye Res. 2008 May;33(5):421-7.

36-The effect of ethyl pyruvate on oxidative stress in intestine and bacterial translocation after thermal injury. (SCI) Karabeyoğlu M, Unal B, Bozkurt B, Dolapçi I, Bilgihan A, Karabeyoğlu I, Cengiz O.
J Surg Res. 2008 Jan;144(1):59-63. 

37-Advanced oxidation protein products are increased in women with polycystic ovary syndrome: relationship with traditional and nontraditional cardiovascular risk factors in patients with polycystic ovary syndrome. (SCI) 
    Kaya C, Erkan AF, Cengiz SD, Dünder I, Demirel OE, Bilgihan A.
Fertil Steril. 2009 Oct;92(4):1372-7

38- Effects of CO(2) pneumoperitoneum on anastomotic healing in rats receiving preoperative 5-fluorouracil neoadjuvant chemotherapy. (SCI-Exp) 
Ulas M, Ozer I, Ercan M, Ozogul YB, Bostanci EB, Keklik TT, Turkcu UO, Bilgihan A, Akoglu M. 
J.Invest Surg. 2009 Nov-Dec;22(6):413-8.

39- Effects of carbon dioxide pneumoperitoneum on hepatic function in obstructive jaundice: an experimental study in a rat model. (SCI-Exp)
Bostanci EB, Yol S, Teke Z, Kayaalp C, Sakaogullari Z, Ozel Turkcu U, Bilgihan A, Akoglu M.
Langenbecks Arch Surg. 2010 Aug;395(6):667-76. 

40- Carnosine supplementation protects rat brain tissue against ethanol-induced oxidative stress. (SCI) Ozel Turkcu U, Bilgihan A, Biberoglu G, Mertoglu Caglar O.
Mol Cell Biochem. 2010 Jun;339(12):55-61.

41- Cardiovascular risk assessment with oxidised LDL measurement in postmenopausal women receiving intranasal estrogen replacement therapy. (SCI-Exp)
Kurdoglu M1, Yildirim M, Kurdoglu Z, Erdem A, Erdem M, Bilgihan A, Goktas B.
Gynecol Endocrinol. 2011 Aug;27(8):551-7.

42-Serum levels of advanced oxidation protein products, malonyldialdehyde, and total radical trapping antioxidant parameter in patients with chronic hepatitis C. (SCI-Exp) 
Ozenırler S, Erkan G, Gülbahar O, Bostankolu O, Ozbaş Demırel O, Bilgihan A, Akyol G.
Turk J Gastroenterol. 2011 Feb;22(1):47-53.

43- Effects of thyroid hormone supplementation on anastomotic healing after segmental colonic resection. (SCI) 
Karaman K, Bostanci EB, Dincer N, Ulas M, Ozer I, Dalgic T, Ercin U, Bilgihan A, Ginis Z, Akoglu M.
J Surg Res. 2012 Aug;176(2):460-7.

44- The Effect of zinc on ethanol-induced oxidative stress in rat liver. (SCI-Exp) 
Mertoğlu Çağlar Ö, Bilgihan A,Özel Türkçü U, Biberoğlu G, Take G.
Turk J Biochem 2012 37(4):104-110.

45- Increased plasma levels of advanced oxidation protein products (AOPP) as a marker for oxidative stress in patients with active ulcerative colitis. (SCI) 
Alagozlu H, Gorgul A, Bilgihan A, Tuncer C, Unal S. 
Clin Res Hepatol Gastroenterol. 2013 Feb;37(1):80-5.

46- Effects of dexamethasone and pheniramine hydrogen maleate on stress response in patients undergoing elective laparoscopic cholecystectomy. (SCI) 
Karaman K, Bostanci EB, Aksoy E, Ulas M, Yigit T, Erdemli MO, Ercin U, Bilgihan A, Saydam G, Akoglu M.
Am J Surg. 2013 Feb;205(2):213-9.


47- The effects of Pycnogenol(®) on colon anastomotic healing in rats given preoperative irradiation. (SCI-Exp) 
Değer KC, Şeker A, Özer I, Bostancı EB, Dalgıç T, Akmansu M, Ekinci Ö, Erçin U, Bilgihan A, Akoğlu M.
Int J Surg. 2013;11(9):983-8.

48- Effects of β-glucan on colon anastomotic healing in rats given preoperative irradiation. (SCI-Exp)
Seker A, Deger KC, Bostanci EB, Ozer I, Dalgic T, Bilgihan A, Akmansu M, Ekinci O, Ercin U, Akoglu M.
J Invest Surg. 2014 Jun;27(3):155-62

49- The relationship between advanced oxidation protein products (AOPP) and biochemical and histopathological findings in patients with nonalcoholic steatohepatitis. (SCI-Exp) A
Ozenirler S, Erkan G, Konca Degertekin C, Ercin U, Cengiz M, Bilgihan A, Yilmaz G, Akyol G.
J Dig Dis. 2014 Mar;15(3):131-6.

50- Increased collagen maturity with sildenafil citrate: experimental high risk colonic anastomosis model. (SCI-Exp)
Cakir T, Ozer I, Bostanci EB, Keklik TT, Ercin U, Bilgihan A, Akoglu M.
Int J Surg. 2015 Jan;13:152-6.

51- Can Riboflavin Penetrate Stroma Without Disrupting Integrity of Corneal Epithelium in Rabbits? Iontophoresis and Ultraperformance Liquid Chromatography With Electrospray Ionization Tandem Mass Spectrometry. (SCI) 
Novruzlu Ş, Türkcü ÜÖ, Kvrak İ, Kvrak Ş, Yüksel E, Deniz NG, Bilgihan A, Bilgihan K.
Cornea. 2015 Aug;34(8):932-6.

52- Endothelial Dysfunction In Patients With Asymptomatic Primer Hyperparathyroidism(SCI-Exp)
B. Aktas Yilmaz, F. Balos Toruner, A. Akyel, U. Ercın, C. Konca Değertekin, Ö. Turhan İyidir, Y. Tavil, A. Bilgihan, M. Arslan
Acta Endocrinologica (Buc), 2015, 11(4): 482-488.

53- Protein Oxidation Levels After Different Corneal Collagen Cross-Linking Methods. (SCI)
Turkcu UO, Yuksel N, Novruzlu S, Yalinbas D, Bilgihan A, Bilgihan K. Atıf sayısı:1
Cornea. 2016 Mar;35(3):388-91.


54- Comparison of Aqueous Humor Nitric Oxide Levels After Different Corneal Collagen Cross-Linking Methods. (SCI)
Yuksel N, Ozel-Turkcu U, Yalinbas D, Novruzlu S, Bilgihan A, Bilgihan K.
Curr Eye Res. 2016 Dec;41(12):1539-1542.


55- Serum and Aqueous Humor Levels of Fetuin-A in Pseudoexfoliation Syndrome.
Yuksel N, Takmaz T, Ozel Turkcu U, Ergin M, Altinkaynak H, Bilgihan A.
Curr Eye Res. 2017 Oct;42(10):1378-1381.

56-Aqueous humor pentraxin-3 levels in patients with diabetes mellitus.
Mutlu M, Yuksel N, Takmaz T, Dincel AS, Bilgihan A, Altınkaynak H.
Eye (Lond). 2017 Oct;31(10):1463-1467.

57- Angiopoietin-like protein 2 and angiopoietin-like protein 6 levels in patients with nonalcoholic fatty liver disease.
Erkan G, Muratoglu S, Ercin U, Bilgihan A.
Arch Med Sci. 2018 Jun;14(4):781-787.- 

58-The Effect of Sildenafil on Selenite-Induced Cataract in Rats.
Atalay HT, Ucgul AY, Turkcu UO, Ozmen MC, Yilmaz S, Bilgihan A.
Curr Eye Res. 2020 Sep;45(9):1082-1088. 

59-Singlet oxygen formation during accelerated and hyperaccelerated corneal cross-linking: in vitro study.
Ercin U, Aribas YK, Tefon Aribas AB, Bilgihan A, Bilgihan K.
Eye (Lond). 2021 Nov;35(11):3147-3151.

60-Comparison of biochemical and immunological biomarker levels of patients with COVID-19 with healthy individuals Ercin U, Aribas ET, Tuncbilek S, Kaya C, Sepici Dincel A, Bilgihan A, Tekeli ME
Turk J Biochem 2021; 46(4): 367–375

61- Iontophoresis Corneal Cross-linking With Oxygen Supplementation in Ovine Eyes.
Aribas YK, Tefon Aribas AB, Ercin U, Sarıkaya B, Bilgihan A, Bilgihan K.
J Refract Surg. 2022 Oct;38(10):674-681.


Articles published in other international peer-reviewed journals:
1- The effect of deferoxamine on brain lipide peroxide levels and Na-K ATPase activity following experimental subarachnoid hemorrhage
Bilgihan A,Türközkan N,Arıcıoğlu A,Aykol Ş,Çevik C,Görsel M.
Gen Pharmacol 25:495-97,1994    

2- The Effect of 2-chloroadenosine on the ATP level and Na-K ATP ase activity in experimental brain ischemia of gerbil.
Türközkan N, Aykol Ş, Bilgihan A, Yavuz Ö, Çaycı B, Doğulu F.
Gen Pharmacol 27(1):165-166,1996

3-The effect of different doses of epidermal growth factor on liver ornithine decarboxylase and Na-K ATP ase activities in newborn rats.
Bilgihan A, Turkozkan N, İşman F, Kılınç M, Demirsoy S.
Gen. Pharmacol. 31(2):261-263,1998

4- Antithrombin III prevents 60 min warm intestinal ischemia reperfusion injury in rats. 
Özden  A, Tetik C, Bilgihan A, Calli N, Bostancı B, Yis Ö, Düzcan E. 
Res Exp Med (Berl).198(5):237-246,1999 

5- The beneficial effect of 2’-deoxycoformycin in renal ischemia-reperfusion is mediated both by preservation of tissue ATP and inhibition of lipid peroxidation. 
Bor V, Durmuş O, Bilgihan A, Çevik C, Türközkan N.
Int J Clin Lab Res 29:75-79,1999.

6- Antithrombin III reduces renal ischemia-reperfusion injury in rats. 
Ozden A, Sarıoğlu A, Demirkan NC, Bilgihan A, Duzcan E
Res Exp Med (Berl)200(3);195-203 , 2001

7- Effects of two different high doses of irradiation on antioxidant system in the liver of guinea pigs. Güney Y., Bukan N, Dizman A, Hiçsönmez A, Bilgihan A.
Exp Oncol 2004 26(1):71-74

8- The relationship between serum cytokine levels with obesity and obstructive sleep apnea syndromeCiftci TU, Kokturk O, Bukan N, Bilgihan A.
Cytokine. 2004 Oct 21;28(2):87-91.

9-Carnosine may reduce lung injury caused by radiation therapy. Guney Y, Turkcu UO, Hicsonmez A, Andrieu MN, Guney HZ, Bilgihan A, Kurtman C. 
Med Hypotheses. 2006;66(5):957-9.

10- Advanced oxidation protein products and malondialdehyde - the new biological markers of oxidative stress - are elevated in postmenopausal women. 
Cakir T, Goktas B, Mutlu MF1, Mutlu I, Bilgihan A, Erdem M, Erdem A.
Ginekol Pol. 2016;87(5):321-5.

Papers presented at international scientific meetings and published in the proceedings. (Proceedings)

1-Comparison of  uveitis induced by interleukin-8 (IL-8) and endotoxin in rabbits.
Akduman L, Kaplan H.J, Ataoğlu Ö, Bilgihan A, Hasanreisoğlu B.
Investigative Ophthalmology and Visual Science Annual Meeting, 3 May 1994-USA

2-Dynamic radionuclide imaging and determination of MDA in the observation of the effects of halothane and isoflurane: An experimental study.
Babacan A, Bilgihan A, Kaya K, Öcal E, Günaydın B, İnanır S, Karadenizli Y.
European Society of Anaesthesiologists Annual Congress, 29 April-3May 1995, Paris-FRANCE

3-Corneal aldehyde dehydrogenase and gluatahione S-transferase activity after excimer laser keratectomy in guinea pigs.
Bilgihan A, Bilgihan K, Hasanreisoğlu B, Türközkan N.
International Congress on Free Radicals in Health and Disease 6-10 Sept. 1995, İstanbul-TURKEY. 

4- Effects of training on liver glutathione peroxidase and glutathione S-transferase activities in young mice.
Şaşmaz G, Kılıç N, Malhatun E, Bilgihan A.
8th Biennial Meeting International Society for Free Radical Research 1-5 October 1996, Barcelona-SPAIN

5- The effect of vitamin E on free radical mediated adriamycin toxicity in guinea pig kidney.
Türközkan N, Elbeg Ş, Bilgihan A.
8th Biennial Meeting International Society for Free Radical Research 1-5 October 1996, Barcelona-SPAIN

6-The effects of K+ channel openers on indomethacin induced gastric mucosal injury and  myeloperoxidase activity in rats.
Uydeş-Doğan B.S, Bilgihan A, Türközkan N, Kanzık İ, Akar F.
XXXIII. International Congress of Physiological Sciences 30 June-5 July 1997, St.Petersburg

7- Role of High Dose Lidocaine in Diabetic Neuropathic Pain.
Çelebi H, Bozkırlı F,Günaydın B, Bilgihan A.
7th. Europain Conference on Pain Research. Dolor Investigation, Clinica and Terapeutica Volume 14, Supp.III, 1999.

8- The effect of intestinal ischaemia reperfusion injury in obstructive jaundice 
Yüksek Y.N,  Koloğlu M, Reis E, Dolapçı M, Bilgihan A, Kama N.A.
Eurosurgery 2000 ,20-24 June 2000 ,Istanbul Convention and Exhibition Center 
(ICEC)-TURKEY

9- The serum levels of vitamins A,C,E,beta carotene, selenium, and zinc in patients 
    with Behçet’s disease:A controlled study 
    Erel A , Özsoy E,  Biberoğlu G, Bilgihan A, Hasanoğlu A, Yis Ö,  Atahan O, Oruk S. 
    3rd Congress of The Mediterranean Association of Dermatology, 23-27 May,2000 
    Kemer-Antalya/TURKEY

10- The total malondialdehyde levels and superoxide dismutase activities sera of the  quinea pigs after whole body irradiation.
       Mertoglu Ö,  Bilgihan A, Guney Y, Biberoglu G, Polat M.
2nd International Meeting on Free Radicals in Health and Disease: Role of Oxidants and Antioxidants in the Regulation of Chronic Diseases
 8-12 May, 2002  Istanbul-TURKEY

11-The effect of excimer laser keratectomy on corneal glutathione peroxidase activities and aqueous humour selenium levels in rabbits.
Yis Ö, Bilgihan A, Bilgihan K, Yis N.Ş, Hasanreisoglu B.
2nd International Meeting on Free Radicals in Health and Disease: Role of Oxidants and Antioxidants in the Regulation of Chronic Diseases
 8-12 May, 2002  Istanbul-TURKEY

12- Placental lipid peroxidation and SOD activities in normal and pregnancies with IUGR
Güney Y,  Dede S,  Erdem F, Dede H, Koca C, Dilbaz B, Bilgihan A.
2nd International Meeting on Free Radicals in Health and Disease: Role of Oxidants and Antioxidants in the Regulation of Chronic Diseases
 8-12 May, 2002  Istanbul-TURKEY

13-Serum malondialdehyde levels and superoxide dismutase activities in pulmonary tuberculosis and lung cancers.
Guney Y, Bilgihan A,.Ciftci T.U, Cimen F, Coskun O.
2nd International Meeting on Free Radicals in Health and Disease: Role of Oxidants and Antioxidants in the Regulation of Chronic Diseases
 8-12 May, 2002  Istanbul-TURKEY

14- Placental free oxygen radicals in fetal distress.
Dede S, Koca C,  Guney Y, Dede H, Dilbaz B, Bilgihan A.
2nd International Meeting on Free Radicals in Health and Disease: Role of Oxidants and Antioxidants in the Regulation of Chronic Diseases
 8-12 May, 2002  Istanbul-TURKEY

15-Kidney tissue tolerance for irradiation; an experimental study.
Bukan  N,  Güney Y, Hiçsönmez A,  Bilgihan A.
2nd International Meeting on Free Radicals in Health and Disease: Role of Oxidants and Antioxidants in the Regulation of Chronic Diseases
 8-12 May, 2002  Istanbul-TURKEY

16- Effects of sublethal and lethal doses of irradiation on antioxidant system in the liver of guinea pigs.
Güney Y, Bukan N, Dizman A,  Bilgihan A.
2nd International Meeting on Free Radicals in Health and Disease: Role of Oxidants and Antioxidants in the Regulation of Chronic Diseases
 8-12 May, 2002  Istanbul-TURKEY

17-Effects of topical vitamin E on corneal superoxide dismutase, glutathione peroxidase activities and polymorphonuclear leucocyte infiltration after photorefractive keratectomy.
Bilgihan A, Bilgihan K, Yis Ö, Sezer C, Akyol G, Hasanreisoğlu B.
XX Congress of the ESCRS 7-11th September 2002-NİCE

18- Does ELF magnetic field effect the myeloperoxidase(MPO) activity in the lung?
Canseven AG, Özel U, Bilgihan A., Seyhan N.
Sensivity of Children to Electromagnetic fields Workshop 9-10 June –İstanbul, 2004

19- The effect of ELF magnetic field exposure on kidney myeploperoxidase (MPO) activity.
Canseven AG, Özel U, Bilgihan A., Seyhan N.
13th Balkan Biochemical Biophysical days and Meeting on Metabolic Disorders 12-15 October Kuşadası, 2003

20- Conventional inflammation and oxidative stress markers of the nonalcoholic fattyn liver disease diagnosed patients. Muratoğlu S, Bilgihan A, Değertekin B, Erkan G, Erçin U, Çalışkan A.
The Febs Journal 2015, 282(sup 1):147

 

Written international books or chapters in books:
1- Bölüm 10 “Kolesterol”, Biyokimya; Olgu Sunumlu Yaklaşım, 
Ankara:Palme Yayıncılık(2000),s.332-355, 
Çeviri Editörü Nilgün Altan(Prof.Dr.):Montgomery,Conway,Spector,Chappel,
Biochemistry;A Case Oriented Approach.6th Ed.1996

2- Bölüm 5 ; Amino asitler, Peptitler ve Proteinler: Lehninger Biyokimyanın İlkeleri,Ankara, Palme Yayıncılık, 2005, Editör;Nedret Kılıç (Prof.Dr) 1152 s, David L.Nelson, Michael M.Cox, Lehninger Principles of Biochemistry, 3rd edition,2000

3-Bölüm 11 Amino asitler ve Proteinler.  Klinik Biyokimya Prensipler, Teknikler ve Korelasyonlar Akademisyen Tıp Kitabevi, 2016. Editör Filiz Akbıyık(Prof.Dr.) 740s. Bishop M.L.Fody E.P. Schoeff L.E. Clinical Chemistry Principles, Techniques and Correlations 7 th edition, 2013

4- Bölüm 33 Beslenmenin değerlendirilmesi. Klinik Biyokimya Prensipler, Teknikler ve Korelasyonlar Akademisyen Tıp Kitabevi, 2016. Editör Filiz Akbıyık(Prof.Dr.) 740s. Bishop M.L.Fody E.P. Schoeff L.E. Clinical Chemistry Principles, Techniques and Correlations 7 th edition, 2013

Articles published in national peer-reviewed journals:
1-Protective effects of verapamil on experimental ischemia-reperfusion induced liver
 injury in cirrhotic rats.
Ferahköşe Z, Nurlu H, Menteş B, Türközkan N, Bilgihan A, Çaycı B.
Marmara Medical Journal 7:81-85, 1994

2-Ratlarda intestinal iskemi ve reperfüzyon hasarında L-Carnitin’in Etkisi.
Özden A, Kargıcı H, Bilgihan A, Özercan R, İlhan N, Türközkan N.
Çağdaş Cerrahi Dergisi 8:209-213, 1994

3-Retina dekolmanı ve serbest oksijen radikalleri
Bilgihan K, Bilgihan A, Akata F, Akbatur H, Or M, Hasanreisoğlu B. 
Ret-Vit 1:191-196, 1994

4-Total parenteral nutrisyon alan hastalarda MCT/LCT ve LCT infüzyonunun eritrosit lipid peroksidasyonuna etkisi.
Koz M, Gören A, Gündoğdu H, Erbaş D, Bilgihan A, Arıcıoğlu A.
MN Klinik Bilimler 1(9): 1-3, 1995

5-Romatoid artrit hastalarında eritrosit glutatyon peroksidaz, malondialdehit ve serum selenium değerlerinin sağlıklı bireylerle karşılaştırılması.
Çubukçu S, Taş N, Bilgihan A, Arıcıoğlu A.
Romatizma Dergisi 10(3):124-127, 1995

6-Etonelle oluşan mide mukoza hasarında nitrik oksitin koruyucu etkisi.
Özden A, Sungurtekin U, Bilgihan A, Özercan R, Neşşar M, Türközkan N.
Ulusal Cerrahi Dergisi 12(1):31-36, 1996

7-Ursodeoksikolik asid kullanılan bir komplike gebeliğin intrahepatik kolestazı vakası.
Çorakçı A, Karabacak O, Himmetoğlu Ö, Bilgihan A, Erdem A, Eskendari R.
Jinekoloji ve Obstetrik Bülteni 7(3):120-123, 1998

8- Kronik üremili hastalarda hemodializden once ve sonra serum lipid peroksit ve serbest yağ asidi değişimlerinin incelenmesi.
Yavuz Ö, Bilgihan A, Ongun Ö, Sindel Ş, Arıcıoğlu A.
A.İ.B.U. Medical Journal 1(1):18-21, 1999


9-Kolelityazisli olgularda serum bakır, çinko düzeyleri ve superoksit dismutaz aktivitesi.
Özel Ü, Bilgihan A, Dolapçı M, Saryal M, Tastı Ç, Kama N.A. 
T Klin Tıp Bilimleri  21:488-492, 2001

10-Nitric oxide level of aqueous humour after photorecractive keratectomy in guinea pigs.
 Bilgihan A, Bilgihan K, Erbaş D, Yis Ö, Hasanreisoğlu B.
Gazi Medical Journal 12:55-58, 2001

11- Ubikitin Sistem
Güney Y, Bilgihan A.
Turkiye Klinikleri J Med Sci 2002, 22:616-619

12-Total malondialdehyde levels and superoxide dismutase activities in the sera of guinea pigs after whole-body irradiation.
Mertoğlu Ö, Bilgihan A, Güney Y, Biberoğlu G, Polat M.
Gazi Medical Journal 14:7-10,2003-12-19

13- Serum     malondialdehyde levels and superoxide dismutase activities in pulmonary tuberculosis and lung cancers 
Güney Y, Bilgihan A.,Çiftçi T.U., Çimen F., Coşkun Ö. A.Ü.Dikimevi SMYO Dergisi 6(2).2004,33-38     

14-The role of superoxide dismutase activity and malondialdehyde levels in the differentiation of benign-malign pleural effusion. 
Çiftçi T.U. Güney Y.Bilgihan A.Çimen F. A.Ü.Dikimevi SMYO Dergisi 6(2).2004,39-43    

15- Serum AOPP, selenium and vitamin E levels after irradiation
.Güney Y, Özel Ü, Mertoğlu Ö, Bilgihan A, Hiçsönmez A, Andrieu Nalça M, Kurtman C. Turkish Journal of Cancer, 36 (1): 19-22, 2006.

16- Sıçan Akciger Dokusunda Tek Doz İyonize Radyasyonun ve Melatonin Tedavisinin Gündüz ve Gece Etkileri 
Guney Y, Uluoglu C, Hicsonmez A, Ozel Turkcu U, Ozbey G, Bilgihan A, Nalca Andrieu M,Guney HZ, Zengil H. 
    Turk J Biochem 2008 33(3):104-110.
    

Projects:
1-Gazi Üniversitesi 01/99-07 Kod.No’lu“Excimer laser keratektomi sonrası kornea glutatyon döngüsü enzim aktiviteleri ve hümör aköz selenyum” isimli proje sonlandırılmıştır.
2-Gazi   Üniversitesi 01/2002-80 Kod.No’lu “Parkinson hastalarında serum ubiquitin düzeyleri” isimli proje sonlandırılmıştır.
3-TÜBİTAK SBAG-2491 (101S191) Kod. No’lu “ Radyoterapi uygulanmış solid tümörlü hastalarda serum ubiquitin düzeyleri ve antioksidan sistem” isimli proje sonlandırılmıştır.
4- Gazi   Üniversitesi 11/2003-10 Kod.No’lu “Etanolle oluşturulan oksidatif streste rat beyin dokusuna antioksidan olan karnozinin etkileri” isimli proje sonlandırılmıştır.
5- Gazi   Üniversitesi 01/2008-40 Kod No’lu "Mast hücre triptazi ve oksidatif stres parametrelerinin koroner arter hastaliğinin klinik ve anjiografik bulgulari ile ilişkisi” isimli proje sonlandırılmıştır.
6 -Gazi Üniversitesi 01/2009-28 Kod No’lu “Koroner Arter Hastalığında, Kanda Oksidatif Stres Parametreleri ve Selenyum Düzeylerinin Klinik Bulgularla İlişkisi” isimli proje sonlandırılmıştır.
7- Gazi Üniversitesi 01/2012-14 Kod No’lu “Non-alkolik Yağlı Karaciğer Hastalığı Tanılı Bireyler ve Sağlıklı Kontrol Grubu Arasında Serum Anjiopoetin-like protein 2, Anjiopoetin-like protein 6 ve Konvansiyonel İnflamasyon ve Oksidatif Stres Belirteçleri Düzeylerinin Karşılaştırılması“ isimli proje sonlandırılmıştır.
8- Gazi Üniversitesi 01/2012-13 Kod No’lu Anjiopoietin like Protein-2, Anjiopoietin like Protein-6, PCSK9 düzeyleri ve konvansiyonel inflamasyon ve oksidatif stres belirteçlerinin koroner arter hastalığının anjiografik yaygınlık ve ciddiyeti ile ilişkisi isimli proje sonlandırılmıştır.